he is upset that the woman he slept with did not tell him about the sexually transmitted disease she had before they had intercourse, because now he has "bugz on his nugz" (a sexually transmitted disease on his genitals)
2Pac is talking about Bob Dole and Bill Clinton, who he thinks are too old to be able to relate to the younger generation of people who listen to rap, and therefore unable to represent them or do anything for them as president.
Wayne is saying he does not know history, he knows about making money. He only knows about Benjamin Franklin because his face is on the $100 dollar bill.
He's saying someone gave him the hot beat. When he says diesel it's something similar to fire (hot beat), also talking about diesel gas which goes into the F-350 pickup truck.
The correct explantion is as such: 4-matic refers to either a .40 or .45 caliber semi-automatic gun, crack means in this case shoot and penetrate the... cabbage which refers to someones head
you stole part of someone's song (from a record) and then played it repeatedly and may have altered it a bit and are using it in your song. this is called "sampling" and usually can't be done without permission
drive my expensive BWM 745 car on a sunny day (most likely a convertible with the top down to get attention). as far as the 745, the "7" (7-series) refers to it being larger than a 5- or 3-series, and the "45" represents its 4.5-Liter engine displacement.